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Pink-eyed dilution, a coat color mutation in the Japanese field vole (Microtus montebelli)
Jikken Dobutsu. Experimental Animals
|July 1, 1991
Abstract:
Inheritance of dilute coat color with pink eye in the Japanese field vole (Microtus montebelli) was investigated by mating of the dilute mutant with a normal agouti vole and a white vole. As the results, it was cleared that an autosomal recessive gene p is responsible for the pink-eyed dilution in M. montebelli.
Insights
A single autosomal recessive gene, designated p, controls the dilute coat color and pink eye in Japanese field voles (Microtus montebelli). This finding clarifies the genetic basis of this specific coat coloration trait in the species.
Area of Science:
- Genetics
- Animal Biology
- Mammalian Genetics
Background:
- Coat color genetics in mammals is complex.
- Understanding inheritance patterns is crucial for evolutionary and developmental biology.
- The Japanese field vole (Microtus montebelli) presents a unique case for coat color studies.
Purpose of the Study:
- To investigate the inheritance pattern of dilute coat color and pink eye in Microtus montebelli.
- To identify the specific gene responsible for the observed phenotype.
Main Methods:
- Controlled breeding experiments were conducted.
- Mating involved a dilute coat color mutant with normal agouti and white voles.
- Phenotypic segregation analysis was performed.
Main Results:
- The dilute coat color and pink eye trait segregated in a manner consistent with Mendelian inheritance.
- A single gene was identified as the cause of the phenotype.
Conclusions:
- An autosomal recessive gene, denoted as 'p', is responsible for the pink-eyed dilution in Microtus montebelli.
- This research elucidates a fundamental aspect of Japanese field vole coat genetics.