Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ending Relationships

Ending Relationships

The dissolution of intimate relationships presents complex emotional and psychological challenges, particularly when emotional bonds are strong, the relationship is long-standing, and perceived alternatives are limited. This distress often intensifies in romantic breakups, where the initiator may experience greater turmoil than the rejected partner. Contributing factors include residual attachment, guilt over causing pain, and uncertainty about how to manage the situation. The stress is further...

Bonanno's Theory of Grieving

Bonanno's Theory of Grieving

Grieving is a complex psychological and emotional process that varies significantly among individuals. George Bonanno's research on bereavement identified four distinct patterns of grieving, offering a nuanced understanding of how people cope with significant loss, such as the death of a spouse, over extended periods. These patterns — resilience, recovery, chronic dysfunction, and delayed grief — highlight the diversity in emotional responses and adaptive mechanisms.
Resilience
The resilience...

First Derivative Test: Problem Solving

First Derivative Test: Problem Solving

Imagine an asset price that crashes to a low point, rebounds sharply as bargain-hunters step in, and then gradually declines. Such behavior can be modeled with a smooth function whose turning points represent locally overvalued and undervalued regions. A convenient example that captures rebound followed by decay is:The high and low points of this curve are identified using the first derivative test, which determines where the function changes from increasing to decreasing or vice versa. To...

Classification of Illness

Classification of Illness

The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe and...

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The Darzi review distributes blame effectively.

BMJ (Clinical research ed.)·2024

Same author

Unpicking the general election manifestos on health and care.

BMJ (Clinical research ed.)·2024

Same author

Steve Barclay's legacy as health secretary.

BMJ (Clinical research ed.)·2023

Same author

What we learnt from the Matt Hancock WhatsApp revelations.

BMJ (Clinical research ed.)·2023

Same author

Labour pains left behind by a united and confident party conference.

BMJ (Clinical research ed.)·2022

Same author

Exit means exit for Boris Johnson?

BMJ (Clinical research ed.)·2022

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Recession. When good times turn bad.

The Health Service Journal

|January 22, 2009

Summary

Government spending cuts have historically strained healthcare resources, leading to service limitations. Modern financial management may better equip the National Health Service (NHS) for future resource challenges.

Area of Science:

Health economics
Public policy
Healthcare management

Background:

Historical analysis of UK government fiscal policies and their impact on healthcare infrastructure.
Examination of resource allocation challenges within the National Health Service (NHS) across different decades.

Observation:

The 1973-74 recession led to significant public spending reductions, curtailing hospital construction.
The 1990s characterized by "desperation" in the health service due to under-resourcing.

Findings:

Recurrent patterns of under-resourcing in the NHS linked to economic downturns and public spending cuts.
Despite historical challenges, improved financial management offers a potential buffer for the NHS.

Implications:

More Related Videos

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

Published on: August 24, 2012

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Related Experiment Videos

Last Updated: Jun 26, 2026

A New Method for Inducing a Depression-Like Behavior in Rats

A New Method for Inducing a Depression-Like Behavior in Rats

Published on: February 22, 2018

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

Extinction Training During the Reconsolidation Window Prevents Recovery of Fear

Published on: August 24, 2012

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data

Published on: December 9, 2015

Healthcare systems must anticipate and plan for periods of reduced public funding.
Enhanced financial stewardship is crucial for maintaining healthcare service delivery amidst economic volatility.