Use of anterior segment optical coherence tomography to assess secondary glaucoma after penetrating keratoplasty
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Updated: Jun 26, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
Jocelyn Chua1, Jodhbir S Mehta, Donald T H Tan
1Cornea and External Disease Service, Singapore National Eye Centre, Singapore. jocelynchua77@yahoo.com
Purpose:
To describe the use of anterior segment optical coherence tomography (AS-OCT) in the evaluation of a patient with raised intraocular pressures after penetrating keratoplasty.
Methods:
A 52-year-old Indian male with bilateral keratoconus underwent multiple penetrating keratoplasties because of repeated episodes of endothelial rejection and graft failure. He also had secondary glaucoma bilaterally for which he underwent bilateral posterior implantation of glaucoma drainage device. During the early postoperative period after a repeat right penetrating keratoplasty with anterior synechiolysis, his right intraocular pressure was persistently raised. The AS-OCT was used to aid in the assessment of the patient.
Results:
The AS-OCT showed obstruction of the glaucoma drainage device by iris tissue and enabled precise placement of the iridectomy immediately overlying the tube orifice.
Conclusions:
The AS-OCT is a useful investigative tool that enables a better evaluation of the structures within the AS. The noncontact nature of the AS-OCT also makes it suitable in postpenetrating keratoplasty eyes where undue pressure on the corneal graft should be avoided.
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