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Published on: April 28, 2013
Revascularisation for a poorly functioning solitary kidney
1Vascular Surgery Unit, Ichilov Hospital, Tel-Aviv Sourasky Medical Center, Israel.
Insights
Surgical revascularization effectively treats renovascular disease in solitary kidneys, improving function and reducing dialysis needs. Percutaneous transluminal angioplasty (PTA) is not recommended for these challenging cases.
Area of Science:
- Nephrology
- Vascular Surgery
- Cardiology
Background:
- Renovascular disease in a solitary kidney presents significant management challenges.
- Previous percutaneous transluminal angioplasty (PTA) attempts were unsuccessful in most patients.
- Preoperative serum creatinine levels indicated impaired kidney function.
Purpose of the Study:
- To evaluate the efficacy and safety of surgical revascularization for renovascular disease in patients with a solitary kidney.
- To compare surgical outcomes with previous unsuccessful PTA interventions.
Main Methods:
- Six patients with solitary kidney renovascular disease underwent surgical revascularization.
- Procedures included aortorenal bypass (saphenous vein or PTFE) and transaortic renal endarterectomy.
- One patient had simultaneous aortic aneurysm repair.
Main Results:
- No mortality or major complications were observed.
- All patients showed improved postoperative serum creatinine and blood pressure.
- Four patients discontinued antihypertensive medication; two required reduced doses.
Conclusions:
- Surgical revascularization is a safe and effective treatment for renovascular disease in solitary kidneys.
- An aggressive surgical approach is recommended over PTA for this patient group.
- Improved solitary kidney function can potentially eliminate the need for hemodialysis.
Abstract:
Renovascular disease in a solitary kidney is a difficult and challenging problem. In six patients, with a mean age of 62 years, revascularisation was undertaken. In four of them, one to three attempts at PTA were made before the operation but all were unsuccessful. The preoperative mean serum creatine (Cr) was 3.52 mg% (range 2.5-5.5). The stenoses were caused by atherosclerosis in five cases and fibromuscular dysplasia (FMD) in one. Two methods of revascularisation were used: aortorenal bypass with saphenous vein (three patients) or PTFE (two patients), and transaortic renal endarterectomy with a venous patch (one patient). One patient with an aortic aneurysm underwent simultaneous aortic repair with a PTFE graft. There was no mortality or major complications in our series and no patient suffered acute tubular necrosis (ATN) after surgery. The mean follow-up period was 51 months (15-84 months). Postoperative Cr and blood pressure improved in all patients. Four patients no longer required any medication and the other two only needed reduced doses of antihypertensive drugs. Based on our experience of patients with poor single kidney function, we do not recommend PTA in this specific group of patients and suggest an aggressive surgical approach, which can effectively improve solitary kidney function, thus eliminating further haemodialysis.
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