Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids01:21

Drugs for Treatment of Crohn's Disease in IBD Using Glucocorticoids

Glucocorticoids, a class of anti-inflammatory drugs, are pivotal in treating moderate to severe Crohn's disease by inducing remission. They exhibit their anti-inflammatory action by inhibiting the production of inflammatory cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, and chemokines like IL-8. In addition, they reduce the expression of inflammatory cell adhesion molecules and inhibit gene transcription of nitric oxide synthase, phospholipase A2, cyclooxygenase-2 (COX-2),...
Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids01:25

Antiasthma Drugs: Inhaled Corticosteroids and Glucocorticoids

Inhaled corticosteroids (ICS) are anti-inflammatory drugs used primarily in treating persistent asthma and providing long-term maintenance. They target the bronchial mucosa, the lining of the airways, to control inflammation, a critical factor in asthma progression and exacerbation.
ICS work through a multifaceted mechanism of action. They suppress the inflammatory response caused by the proliferation of TH cells. They also reduce the transcription of the IL-2 gene, which is involved in the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[End-of-life conversations].

Nederlands tijdschrift voor geneeskunde·2025
Same author

Predictors of the effects of treatment for shoulder pain: protocol of an individual participant data meta-analysis.

Diagnostic and prognostic research·2019
Same author

Familial Aggregation between the 14th and 21st Century and Type 2 Diabetes Risk in an Isolated Dutch Population.

PloS one·2015
Same author

Radiating low back pain in general practice: incidence, prevalence, diagnosis, and long-term clinical course of illness.

Scandinavian journal of primary health care·2015
Same author

Epidural steroids for lumbosacral radicular syndrome compared to usual care: quality of life and cost utility in general practice.

Archives of physical medicine and rehabilitation·2014
Same author

Steroid injections added to the usual treatment of lumbar radicular syndrome: a pragmatic randomized controlled trial in general practice.

BMC musculoskeletal disorders·2014

Related Experiment Video

Updated: Jun 26, 2026

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
05:18

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

Corticosteroid injection for trigger finger in adults.

Cyriac Peters-Veluthamaningal1, Daniëlle A W M van der Windt, Jan C Winters

  • 1Department of General Practice, University Medical Center Groningen, Antonius Deusinglaan 1, Groningen, Netherlands, 9713 AV. raju@dds.nl.

The Cochrane Database of Systematic Reviews
|January 23, 2009
PubMed
Summary

Corticosteroid injections combined with lidocaine offer superior short-term treatment success for trigger finger compared to lidocaine alone. Evidence is limited due to small study sizes and methodological quality concerns.

More Related Videos

A Standardized Acupotomy Protocol For The Treatment of Tenosynovitis of Hand Flexor Tendons In Human Patients
07:05

A Standardized Acupotomy Protocol For The Treatment of Tenosynovitis of Hand Flexor Tendons In Human Patients

Published on: May 26, 2026

Related Experiment Videos

Last Updated: Jun 26, 2026

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome
05:18

Ultrasound-Guided Needle Release Combined with Corticosteroid Injection for the Treatment of Supinator Syndrome

Published on: May 26, 2023

A Standardized Acupotomy Protocol For The Treatment of Tenosynovitis of Hand Flexor Tendons In Human Patients
07:05

A Standardized Acupotomy Protocol For The Treatment of Tenosynovitis of Hand Flexor Tendons In Human Patients

Published on: May 26, 2026

Area of Science:

  • Orthopedics
  • Musculoskeletal Disorders
  • Pharmacology

Background:

  • Trigger finger, a condition causing hand pain and dysfunction, is often treated with corticosteroid injections.
  • Other treatments include surgery and splinting.

Purpose of the Study:

  • To evaluate the efficacy and safety of corticosteroid injections for treating trigger finger in adults.
  • Key endpoints include treatment success, symptom frequency, finger function, and pain severity.

Main Methods:

  • A systematic review of randomized controlled trials was conducted.
  • Databases searched included CENTRAL, MEDLINE, EMBASE, CINAHL, AMED, and PEDro.
  • Two trials involving 63 participants were selected for analysis.

Main Results:

  • Corticosteroid injections with lidocaine demonstrated greater treatment success at four weeks compared to lidocaine alone (RR 3.15).
  • The number needed to treat was 3, indicating significant benefit.
  • No adverse events or side effects were reported in the included studies.

Conclusions:

  • Corticosteroid injections combined with lidocaine show short-term effectiveness for trigger finger.
  • Evidence quality is limited by small sample sizes and methodological weaknesses in the included trials.
  • Further high-quality research is needed to confirm these findings.