Improved patient survival with concomitant Cox Maze III procedure compared with heart surgery alone

Yves Louagie1, Michel Buche, Philippe Eucher

  • 1Cardiovascular Department, Université Catholique de Louvain, Cliniques Universitaires de Mont-Godinne, Yvoir, Belgium. louagie@chir.ucl.ac.be

Insights

The Cox Maze III procedure combined with heart surgery significantly improves long-term survival for patients with persistent atrial fibrillation. This cardiac surgery approach reduces mortality from heart failure and sudden death.

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Electrophysiology

Background:

  • The Cox Maze procedure is a surgical treatment for atrial fibrillation.
  • Its long-term efficacy when combined with heart surgery requires evaluation.

Purpose of the Study:

  • To assess the long-term benefit of the Cox Maze III procedure combined with heart surgery.
  • To compare survival rates in patients who underwent combined surgery versus heart surgery alone.

Main Methods:

  • A retrospective study comparing 37 patients (Maze group) with 66 controls.
  • All patients had persistent atrial fibrillation preoperatively.
  • Follow-up data was analyzed for survival and rhythm conversion.

Main Results:

  • Five-year survival was 89% in the Maze group vs. 60% in the control group (p=0.008).
  • The Maze procedure independently improved survival (p=0.019) and reduced deaths from heart failure and sudden death.
  • Five-year conversion to sinus rhythm was 91% in the Maze group vs. 33% in controls (p<0.001).

Conclusions:

  • Combining the Cox Maze procedure with heart surgery significantly enhances long-term survival.
  • Restoration of sinus rhythm is a key factor in improved outcomes.
  • The procedure is particularly beneficial for patients with enlarged left atria.
Abstract

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