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A Rodent Model of The Ross Operation: Syngeneic Pulmonary Artery Graft Implantation in A Systemic Position
Published on: April 1, 2022
A single-institution experience with the Ross operation over 11 years
Jürgen O Böhm1, Wolfgang Hemmer, Joachim-Gerd Rein
1Sana Cardiac Surgical Clinic, Stuttgart, Germany. joboehm@z.zgs.de
The Annals of Thoracic Surgery
|January 24, 2009
Summary
The Ross operation offers favorable long-term survival and low mortality for aortic valve pathology. However, reoperation rates for autograft and homograft failure are higher than previously reported.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Cardiac Valve Surgery
Background:
- The Ross operation is the sole autologous aortic valve replacement option.
- It involves double-valve replacement for aortic valve pathology.
- This study details an 11-year experience with the procedure.
Purpose of the Study:
- To evaluate the long-term outcomes of the Ross operation.
- To assess patient survival and freedom from valve-related events.
- To analyze reoperation rates and complications over an 11-year period.
Main Methods:
- A cohort of 467 patients underwent the Ross operation before August 2006.
- The right ventricular outflow tract was reconstructed using a cryopreserved pulmonary homograft.
- Follow-up data was 94.4% complete for survival and event analysis.
Main Results:
- The 30-day mortality rate was 0.6%.
- At 120 months, Kaplan-Meier survival was 94.4%.
- Freedom from autograft failure was 94.2%, while freedom from homograft dysfunction was 79.3%.
Conclusions:
- The Ross operation demonstrates favorable long-term patient survival and low mortality.
- Reoperation rates for autograft and homograft failure, along with endocarditis, were higher than in prior reports.
- Homograft dysfunction was more prevalent in younger patients.
