Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Hemorrhagic Stroke l: Introduction

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Spatiotemporal Associations Between Cortical Microinfarcts and Cortical Superficial Siderosis in Cerebral Amyloid Angiopathy.

Neurology·2026

Same author

Long-Term Blood Pressure Variability in Cerebral Amyloid Angiopathy is Associated with Ischemic Brain Injury and Cognitive Decline.

Journal of the American Heart Association·2026

Same author

Plasma Amyloid Beta and Tau Associations with Cerebral Amyloid Angiopathy Presence and Severity.

Annals of neurology·2026

Same author

Hemorrhage Pattern and Amyloid Burden in Cerebral Amyloid Angiopathy.

Journal of the American Heart Association·2026

Same author

Extent of Tau and Its Cognitive Implications in Patients With Cerebral Amyloid Angiopathy Without Cognitive Impairment.

Neurology·2026

Same author

Perivascular Space Progression in Patients with Cerebral Amyloid Angiopathy.

European neurology·2026

Same journal

Resolution of expression of concern-Serotonergic pathology and disease burden in the premotor and motor phase of A53T α-synuclein parkinsonism: a cross-sectional study.

The Lancet. Neurology·2026

Same journal

UCL Queen Square Institute of Neurology: 75 years of innovation.

The Lancet. Neurology·2026

Same journal

Correction to Lancet Neurol 2026; 25: 631.

The Lancet. Neurology·2026

Same journal

Epstein-Barr virus and multiple sclerosis: from associations to mechanisms to potential therapies.

The Lancet. Neurology·2026

Same journal

Correction to Lancet Neurol 2025; 24: 740-52.

The Lancet. Neurology·2026

Same journal

Correction to Lancet Neurol 2026; 25: 357-67.

The Lancet. Neurology·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Cerebral microbleeds: a guide to detection and interpretation.

Steven M Greenberg¹, Meike W Vernooij, Charlotte Cordonnier

¹Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. sgreenberg@partners.org

The Lancet. Neurology

|January 24, 2009

Summary

This summary is machine-generated.

Cerebral microbleeds (CMBs) are common in aging and dementia. Newer MRI techniques improve detection, but results depend on imaging methods, influencing interpretation of their role in small-vessel brain disease.

More Related Videos

Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats

Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats

Published on: October 17, 2018

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

Related Experiment Videos

Last Updated: Jun 26, 2026

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats

Sub-acute Cerebral Microhemorrhages Induced by Lipopolysaccharide Injection in Rats

Published on: October 17, 2018

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

Area of Science:

Neuroimaging
Neurology
Radiology

Background:

Cerebral microbleeds (CMBs) are recognized neuroimaging findings in cerebrovascular disease, dementia, and normal aging.
Recent advancements in MRI techniques have significantly improved CMB detection, particularly in elderly populations.

Purpose of the Study:

To review recent developments in MRI methods for detecting cerebral microbleeds (CMBs).
To discuss how MRI technique influences the interpretation of CMB detection and prevalence.
To propose a guide for CMB identification and future research directions.

Main Methods:

Review of recent literature on MRI techniques for cerebral microbleed (CMB) detection.
Analysis of factors influencing CMB detection, including MRI pulse sequence, parameters, resolution, field strength, and post-processing.
Application of sensitive MRI techniques to population-based samples of elderly individuals.

Main Results:

The number of detected cerebral microbleeds (CMBs) is highly dependent on specific MRI characteristics.
Sensitive MRI techniques reveal a high prevalence of CMBs in community-dwelling elderly individuals.
Interpretation of CMBs requires careful consideration of the MRI techniques employed.

Conclusions:

MRI technique is crucial for accurate cerebral microbleed (CMB) detection and interpretation.
CMBs are highly prevalent in the elderly, underscoring their significance in small-vessel brain disease.
Further research is needed to elucidate the role of CMBs as markers and contributors to brain disease.