Joint analysis of differential mobility spectrometer and mass spectrometer features for tuberculosis biomarkers
Meredith G Cunha1, Shirley Hoenigman, Chitra Kanchagar
1Mission Systems Division, Draper Laboratory, Cambridge, MA 02492, USA. mgerber@draper.com
Abstract:
In this article, we present results of recent efforts to identify biomarkers for tuberculosis using a differential mobility spectrometer (DMS). We focus specifically on the capability of exploiting a data collection system that employs a DMS in parallel with a mass spectrometer. This system permits previously developed algorithms for DMS to be used in conjunction with a device considered a gold-standard for chemical identification, making it a unique discovery tool for the determination of biomarkers.
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