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Base lung sound in diffuse interstitial pneumonia analyzed by linear and nonlinear techniques
L Albuerne-Sánchez1, S Charleston-Villalobos, R González-Camarena
1Biomedical Engineering Program, Universidad Autónoma Metropolitana, Mexico City 09340, Mexico. li_alsa@yahoo.com.mx
Summary
Analyzing base lung sounds (BLS) in diffuse interstitial pneumonia reveals differences in healthy individuals and patients. Nonlinear techniques, specifically sample entropy, better distinguished abnormal BLS in patients.
Area of Science:
- Pulmonary Medicine
- Biomedical Engineering
- Acoustics
Background:
- Diffuse interstitial pneumonia is characterized by abnormal lung sounds, primarily crackles.
- Analysis of the underlying base lung sounds (BLS) between crackles has been limited.
- Investigating BLS may offer novel diagnostic insights for interstitial lung diseases.
Purpose of the Study:
- To analyze base lung sounds (BLS) in patients with diffuse interstitial pneumonia and compare them to healthy subjects.
- To evaluate the effectiveness of linear (spectral percentiles) and nonlinear (sample entropy) techniques in differentiating abnormal BLS.
- To determine if BLS analysis can provide independent diagnostic information.
Main Methods:
- Acquired lung sound recordings from 8 healthy subjects and 8 patients with diffuse interstitial pneumonia.
- Analyzed segments of BLS (crackles absent) from four posterior chest locations (apical and basal).
- Applied spectral percentiles and sample entropy (SampEn) to quantify BLS characteristics.
Main Results:
- Sample entropy and spectral percentiles tended to be lower in patients with diffuse interstitial pneumonia.
- Statistically significant differences in BLS were found between groups in the left hemithorax (apical and basal) and right basal region.
- The nonlinear technique (SampEn) demonstrated better discrimination of abnormal BLS compared to spectral percentiles.
Conclusions:
- Base lung sounds (BLS) in diffuse interstitial pneumonia patients show distinct characteristics compared to healthy individuals, particularly when analyzed using nonlinear methods.
- Sample entropy (SampEn) of BLS can provide valuable information for diagnosing diffuse interstitial pneumonia.
- Nonlinear analysis of BLS appears more effective than linear methods for identifying abnormal lung sounds in this condition.
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