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Related Experiment Video

Updated: Jun 26, 2026

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Published on: December 19, 2017

A high resolution, monolithic crystal, PET/MRI detector with DOI positioning capability.

Xiaoli Li¹, Cate Lockhart, Tom K Lewellen

¹University of Washington, Department of Physics, Seattle, USA. lixioli@u.washington.edu

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

|January 24, 2009

Summary

This study introduces a novel PET detector with depth of interaction (DOI) capabilities, using micro-pixel avalanche photodiodes (MAPDs) for enhanced PET/MRI imaging. The design significantly improves spatial resolution compared to conventional detectors.

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Area of Science:

Medical Imaging
Detector Physics

Background:

Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) are powerful imaging modalities.
Integrating PET and MRI offers complementary anatomic and functional information.
Accurate depth of interaction (DOI) measurement is crucial for improving PET image quality.

Purpose of the Study:

To develop a high-resolution, monolithic crystal PET detector with DOI capabilities.
To design a PET detector compatible with MRI scanners for multimodal imaging.
To evaluate the spatial resolution performance of the novel detector design.

Main Methods:

Utilized a novel sensor on the entrance surface (SES) design.
Employed a two-dimensional array of micro-pixel avalanche photodiodes (MAPDs) as sensors.
Performed multi-step simulations to determine intrinsic spatial resolution characteristics.

Main Results:

Achieved intrinsic spatial resolutions of 0.83 mm (X), 0.92 mm (Y), and 1.83 mm (Z/DOI) for a 15 mm LSO crystal detector.
Demonstrated an average improvement of 25% in X, 23% in Y, and 20% in Z compared to conventional designs.
Confirmed MAPDs' suitability for high magnetic field operation in PET/MRI.

Conclusions:

The proposed monolithic crystal PET detector design with SES and MAPDs offers superior spatial resolution and DOI capability.
This design is compatible with MRI scanners, enabling advanced multimodal PET/MRI.
The findings represent a significant advancement in PET detector technology for improved medical imaging.