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Published on: May 13, 2019
A nonenzymatic biosensor based on copper nanoparticles modified electrode for detection of acetylcholine
Ali Jabbari1, Hossein Heli, Maryam Hajjizadeh
1Department of Chemistry, K. N. Toosi University of Technology, Tehran, Iran. jabbari@kntu.ac.ir
Abstract:
The electrocatalytic oxidation of acetylcholine (Ach) on copper microparticles modified carbon paste electrode (m-CPE) and copper nanoparticles-modified carbon paste electrode (n-CPE) was investigated. In the voltammogram recorded using m-CPE, a single anodic peak related to the oxidation of ACh was observed. Using n-CPE, however, two overlapped anodic peaks were observed. The amino acids oxidized on n-CPE at higher rates at lower potentials compared to m-CPE. A nonenzymatic amperometric biosensor was constructed and a simple analysis procedure was developed for the determination of ACh.

