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Related Experiment Video

Updated: Jun 26, 2026

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

Flexible polymer substrate and tungsten microelectrode array for an implantable neural recording system.

Erin Patrick1, Viswanath Sankar, William Rowe

  • 1Department of Electrical and Computer Engineering, University of Florida, Gainesville, FL 32611, USA. ee1@ufl.edu

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
|January 24, 2009
PubMed
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Researchers developed a flexible substrate for neural recording systems. This implantable device features tungsten microwires for brain-machine interfaces, achieving high signal-to-noise ratios in initial tests.

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Materials Science

Background:

  • Developing fully implantable neural recording systems is crucial for advancing brain-machine interfaces (BMIs).
  • Existing systems face challenges in biocompatibility, longevity, and signal fidelity.
  • Flexible substrates offer potential for improved integration and performance.

Purpose of the Study:

  • To describe the fabrication process and performance of a novel substrate for an implantable neural recording system.
  • To evaluate the suitability of hybrid-packaged tungsten microwires on a flexible polymer substrate for intracortical recording.
  • To assess the signal quality and noise characteristics of the developed microelectrode array.

Main Methods:

  • Hybrid packaging of tungsten microwires onto a micromachined flexible polymer substrate.

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Last Updated: Jun 26, 2026

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays
08:54

Chronic Implantation of Multiple Flexible Polymer Electrode Arrays

Published on: October 4, 2019

Fabrication of Ti3C2 MXene Microelectrode Arrays for In Vivo Neural Recording
09:58

Fabrication of Ti3C2 MXene Microelectrode Arrays for In Vivo Neural Recording

Published on: February 12, 2020

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive
06:40

Insertion of Flexible Neural Probes Using Rigid Stiffeners Attached with Biodissolvable Adhesive

Published on: September 27, 2013

  • Fabrication of an intracortical microelectrode array.
  • Benchtop characterization of the microelectrode array.
  • In vivo testing for neural recording performance.

    • Main Results:

    • The microelectrode array demonstrated a noise floor below 2 microV.
    • Acute in vivo recordings achieved a signal-to-noise ratio (SNR) between 9.9 and 17.3 dB.
    • The hybrid fabrication technique proved effective for creating the neural recording substrate.

    Conclusions:

    • The developed flexible substrate with hybrid-packaged tungsten microwires is a viable platform for fully implantable neural recording systems.
    • This approach facilitates the development of advanced brain-machine interfaces.
    • The demonstrated performance metrics support the potential of this technology for future neuroprosthetics and research tools.