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[Reference values in immunodiagnosis: the approach using the Senieur protocol].

D Dekaric, Lj Matijević, A Sabioncello

    Glas. Srpska Akademija Nauka I Umetnosti. Odeljenje Medicinskih Nauka
    |January 1, 1991
    PubMed
    Summary

    Standardizing immunological tests requires strict criteria. The SENIEUR protocol provides these for human studies, enabling age-related immune function analysis.

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    Area of Science:

    • Immunology
    • Gerontology
    • Biomedical Science

    Context:

    • Establishing reference ranges for immunological tests is crucial for accurate clinical interpretation.
    • The European Community's EURAGE Concerted Action Programme developed the SENIEUR protocol.
    • The SENIEUR protocol outlines specific admission criteria for human immunological studies.

    Purpose:

    • To present results on humoral and cellular immunity.
    • To analyze these immune components in relation to age.
    • To apply the SENIEUR protocol admission criteria for standardization.

    Summary:

    • The study evaluated humoral and cellular immunity across different age groups.
    • Participants were selected based on the stringent admission criteria of the SENIEUR protocol.

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  • Results demonstrate age-dependent changes in immune function within a standardized cohort.

    • Impact:

    • Provides a standardized approach for immunological research in aging populations.
    • Facilitates more reliable comparisons of immune function data across studies.
    • Contributes to a better understanding of immune system changes throughout the human lifespan.