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Published on: May 23, 2020
Abnormal mandibular growth and the condylar cartilage
Pertti Pirttiniemi1, Timo Peltomäki, Lukas Müller
1Department of Oral Development and Orthodontics, Institute of Dentistry, University of Oulu, Finland. pertti.pirttiniemi@oulu.fi
This review covers pathological alterations affecting the temporomandibular joint (TMJ) and mandibular growth during childhood and adolescence. It categorizes conditions from congenital malformations to acquired diseases impacting facial development.
Area of Science:
- Craniofacial Biology
- Developmental Biology
- Pediatric Dentistry
Background:
- Mandibular condyle growth deviations impact facial aesthetics and functional occlusion.
- These deviations stem from complex cellular malfunctions.
- Understanding these disorders is crucial for effective treatment.
Purpose of the Study:
- To review recent advancements in understanding pathological alterations of the temporomandibular joint (TMJ).
- To summarize conditions affecting mandibular growth during childhood and adolescence.
- To categorize these disorders for better comprehension.
Main Methods:
- Literature review of recent progress in understanding TMJ pathologies.
- Categorization of pathological conditions affecting mandibular growth.
- Analysis of congenital, primary, and acquired growth disorders.
Main Results:
- Congenital malformations like hemifacial microsomia (HFM) cause severe TMJ growth disturbances.
- Hemimandibular hyperplasia/elongation present obscure but prominent mandibular growth abnormalities.
- Juvenile idiopathic arthritis (JIA) and condylar fractures directly damage TMJ cartilage, affecting growth.
Conclusions:
- Pathological alterations in the TMJ significantly disrupt mandibular growth.
- A clear categorization aids in understanding diverse etiologies of these disorders.
- Further research into cellular mechanisms is needed for targeted interventions.
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