Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
Imaging Studies for Cardiovascular System V: CT01:28

Imaging Studies for Cardiovascular System V: CT

Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The rationale against a "mandatory" extended hepatectomy in perihilar cholangiocarcinoma: meta-analysis.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2026
Same author

Nutritional aspects and quality of life in gastroesophageal cancer patients that underwent colonic interposition.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2026
Same author

Fat malabsorption and reduced exocrine pancreatic function after gastroesophageal cancer surgery.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract·2026
Same author

Timing of adjuvant chemotherapy in patients with pancreatic ductal adenocarcinoma: A nationwide analysis.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2025
Same author

Selection for local treatment and outcomes of surgical resection in patients with synchronous colorectal liver metastases: A nationwide population-based study.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2025
Same author

Early detection and correction of preoperative anemia in patients undergoing colorectal surgery-a prospective study.

Techniques in coloproctology·2025
Same journal

Is there evidence that intranasal ketamine can provide adequate procedural sedation in paediatric patients?

Emergency medicine journal : EMJ·2026
Same journal

Consensus-based definition of paediatric out-of-hospital clinical deterioration: a modified delphi study.

Emergency medicine journal : EMJ·2026
Same journal

Parents' and children's experiences of prehospital care after a child's head injury: a qualitative study.

Emergency medicine journal : EMJ·2026
Same journal

Nurse-delivered intravenous opioids in UK emergency departments: implications for pain standards and practice.

Emergency medicine journal : EMJ·2026
Same journal

Are high doses of naloxone required for nitazene overdoses?

Emergency medicine journal : EMJ·2026
Same journal

A cold, blue leg.

Emergency medicine journal : EMJ·2026
See all related articles

Related Experiment Video

Updated: Jun 26, 2026

Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
06:28

Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis

Published on: September 2, 2025

Interobserver variability in CT scan interpretation for suspected acute appendicitis.

K H in't Hof1, G P Krestin, E W Steijerberg

  • 1Department of Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands. k.inthof@erasmusmc.nl

Emergency Medicine Journal : EMJ
|January 24, 2009
PubMed
Summary
This summary is machine-generated.

Radiologist expertise significantly impacts computed tomography (CT) scan accuracy for diagnosing acute appendicitis. Higher expertise levels improve sensitivity and specificity, making routine CT justified only in centers with experienced radiologists.

Related Experiment Videos

Last Updated: Jun 26, 2026

Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis
06:28

Anterior Cruciate Ligament Transection and Synovial Fluid Lavage in a Rodent Model to Study Joint Inflammation and Posttraumatic Osteoarthritis

Published on: September 2, 2025

Area of Science:

  • Radiology
  • Gastroenterology
  • Surgical Diagnostics

Background:

  • Acute appendicitis is a common surgical emergency.
  • Computed tomography (CT) is frequently used for diagnosis.
  • Interobserver variability in CT interpretation may affect diagnostic accuracy.

Purpose of the Study:

  • To assess interobserver variability in CT scan interpretation for suspected acute appendicitis.
  • To evaluate the impact of radiologist expertise on diagnostic performance.

Main Methods:

  • Prospective study of 103 adult patients with suspected acute appendicitis.
  • Unenhanced helical multislice CT scans were performed.
  • CT scans were interpreted by radiologists with varying expertise levels (Groups A, B, C).
  • Laparoscopy was used as the gold standard for diagnosis.

Main Results:

  • CT diagnosis of appendicitis ranged from 69% (Group A) to 80% (Group C).
  • Sensitivity for appendicitis increased with expertise (81% to 95%).
  • Specificity was high across all groups (94% to 100%).
  • Group C radiologists demonstrated superior performance in diagnosing other abdominal conditions.

Conclusions:

  • Significant interobserver variability exists in CT interpretation for acute appendicitis.
  • Radiologist expertise is crucial for accurate CT diagnosis.
  • Routine CT implementation for suspected appendicitis is recommended only in centers with expert radiologists.