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Related Concept Videos

Centrosome Duplication02:25

Centrosome Duplication

The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
Centrosome Duplication02:25

Centrosome Duplication

The primary microtubule organizing center (MTOC) in animal cells is the centrosome. A centrosome has two cylindrical centrioles at its core. Each centriole consists of nine sets of three microtubules held together by proteins. The centrioles are positioned at right angles to each other and surrounded by a shapeless protein cloud called the pericentriolar matrix, or pericentriolar material (PCM).
To ensure that each daughter cell receives a centrosome after cell division, centrosome duplication...
Centrioles and Centrosomes01:13

Centrioles and Centrosomes

Most animal cells comprise a pair of centrioles together called a centrosome. The cell duplicates its centrosome and contains two centrosomes side-by-side, which begin to move apart during the prophase. As the centrosomes migrate to two different sides of the cell, microtubules start extending from each centrosome toward the other end. The mitotic spindle is composed of the centrosomes and their emerging microtubules.
Near the end of the prophase, also called late prophase or "prometaphase,"...
Chromosomal Theory of Inheritance01:39

Chromosomal Theory of Inheritance

In 1866, Gregor Mendel published the results of his pea plant breeding experiments, providing evidence for predictable patterns in the inheritance of physical characteristics. The significance of his findings was not immediately recognized. In fact, the existence of genes was unknown at the time. Mendel referred to hereditary units as “factors.”
Histone Variants at the Centromere02:30

Histone Variants at the Centromere

Histone variants are the histone proteins with structural and sequence variations. These variants may be regarded as “mutant” forms that replace their canonical histone counterparts in the nucleosomes. Specific post-translational modifications on the histone variants enable further chromatin complexity and regulate tissue-specific gene expression. The most common histone variants are from histone H2A, H2B, and linker histone H1 families. However, several variants of histone H3 variants are also...
Non-nuclear Inheritance01:29

Non-nuclear Inheritance

Most DNA resides in the nucleus of a cell. However, some organelles in the cell cytoplasm⁠—such as chloroplasts and mitochondria⁠—also have their own DNA. These organelles replicate their DNA independently of the nuclear DNA of the cell in which they reside. Non-nuclear inheritance describes the inheritance of genes from structures other than the nucleus.

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Related Experiment Video

Updated: Jun 26, 2026

Isolation and Fluorescence Imaging for Single-particle Reconstruction of Chlamydomonas Centrioles
10:38

Isolation and Fluorescence Imaging for Single-particle Reconstruction of Chlamydomonas Centrioles

Published on: September 21, 2018

Centriole inheritance.

Patricia G Wilson1

  • 1Regenerative Bioscience Center, Department of Animal and Dairy Science, University of Georgia, Athens, Georgia 30602, USA. pgwilson2@earthlink.net

Prion
|January 24, 2009
PubMed
Summary
This summary is machine-generated.

Centrosomes, crucial for cell division, are not essential for proliferation. This review explores recent findings on centriole inheritance in animal cells, challenging long-held beliefs about their permanent nature.

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Quantitative Immunofluorescence Assay to Measure the Variation in Protein Levels at Centrosomes
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Quantitative Immunofluorescence Assay to Measure the Variation in Protein Levels at Centrosomes

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Imaging Centrosomes in Fly Testes
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Imaging Centrosomes in Fly Testes

Published on: September 20, 2013

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Last Updated: Jun 26, 2026

Isolation and Fluorescence Imaging for Single-particle Reconstruction of Chlamydomonas Centrioles
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Isolation and Fluorescence Imaging for Single-particle Reconstruction of Chlamydomonas Centrioles

Published on: September 21, 2018

Quantitative Immunofluorescence Assay to Measure the Variation in Protein Levels at Centrosomes
09:39

Quantitative Immunofluorescence Assay to Measure the Variation in Protein Levels at Centrosomes

Published on: December 20, 2014

Imaging Centrosomes in Fly Testes
09:41

Imaging Centrosomes in Fly Testes

Published on: September 20, 2013

Area of Science:

  • Cell Biology
  • Molecular Biology

Background:

  • Centrosomes, composed of centrioles and pericentriolar matrix, were traditionally viewed as permanent cellular structures.
  • They play a key role in organizing microtubules and assembling the mitotic spindle for chromosome segregation.
  • Centriole duplication and inheritance were thought to follow a template mechanism.

Purpose of the Study:

  • To review recent literature on centriole inheritance in animal cells.
  • To examine the current understanding of centrosome and centriole roles in cell proliferation.

Main Methods:

  • Literature review of recent studies on animal cell biology.
  • Analysis of research on centrosome duplication and inheritance mechanisms.

Main Results:

  • Centrioles and centrosomes are not essential for cell proliferation.
  • The understanding of centriole inheritance is evolving beyond the traditional template model.

Conclusions:

  • Centrosomes are not permanent cellular structures and are dispensable for cell proliferation.
  • Recent research provides new insights into the complex mechanisms of centriole inheritance in animal cells.