Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 26, 2026

Operant Learning of Drosophila at the Torque Meter
17:31

Operant Learning of Drosophila at the Torque Meter

Published on: June 16, 2008

There are many ways to train a fly.

Jena L Pitman1, Shamik DasGupta, Michael J Krashes

  • 1Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

Fly
|January 24, 2009
PubMed
Summary

Fruit flies are powerful models for studying memory. Advanced genetic tools now allow researchers to explore memory genes within functioning neural circuits, making a complete understanding of fly memory achievable.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A 5.3-million-year-old deep-sea whale necropolis in the Diamantina Zone.

Nature·2026
Same author

Semaglutide drives weight loss through cAMP-dependent mechanisms in GLP1R-expressing hindbrain neurons.

Nature metabolism·2026
Same author

A distinct vagus-beta cell neural circuit senses glucose and modulates insulin secretion.

Molecular metabolism·2026
Same author

Retraction Note: Multisensory learning binds neurons into a cross-modal memory engram.

Nature·2026
Same author

High-fat food reinforces risk taking by suppressing defensive neurons.

Current biology : CB·2025
Same author

Cognitive primitives of the insect brain.

Trends in cognitive sciences·2025

Area of Science:

  • Neuroscience
  • Molecular Biology
  • Behavioral Science

Background:

  • The fruit fly, Drosophila melanogaster, has been instrumental in identifying memory genes for over three decades.
  • Recent advancements in genetic tools enable the manipulation of neural activity, shifting focus to the functional neural circuits underlying memory.

Purpose of the Study:

  • To review and summarize various behavioral assays developed for studying memory and plastic behaviors in flies.
  • To provide an overview of the current capabilities for investigating memory in Drosophila, from larvae to adults.

Main Methods:

  • The review synthesizes findings from numerous studies employing diverse assays to probe fly memory.
  • Emphasis is placed on olfactory conditioning paradigms, while acknowledging other methodologies.

More Related Videos

FLEX: Flight Exercise Training Protocol for the Fruit Fly Drosophila
03:47

FLEX: Flight Exercise Training Protocol for the Fruit Fly Drosophila

Published on: October 14, 2025

A Simple Way to Measure Alterations in Reward-seeking Behavior Using Drosophila melanogaster
06:57

A Simple Way to Measure Alterations in Reward-seeking Behavior Using Drosophila melanogaster

Published on: December 15, 2016

Related Experiment Videos

Last Updated: Jun 26, 2026

Operant Learning of Drosophila at the Torque Meter
17:31

Operant Learning of Drosophila at the Torque Meter

Published on: June 16, 2008

FLEX: Flight Exercise Training Protocol for the Fruit Fly Drosophila
03:47

FLEX: Flight Exercise Training Protocol for the Fruit Fly Drosophila

Published on: October 14, 2025

A Simple Way to Measure Alterations in Reward-seeking Behavior Using Drosophila melanogaster
06:57

A Simple Way to Measure Alterations in Reward-seeking Behavior Using Drosophila melanogaster

Published on: December 15, 2016

Main Results:

  • Drosophila larvae and adults display complex behaviors and are amenable to various training protocols.
  • Sophisticated genetic tools allow for the examination of memory genes within the context of neural circuit function.

Conclusions:

  • A comprehensive understanding of biological memory in flies is now a realistic objective.
  • The review aims to equip researchers with knowledge of available assays to encourage further investigation into fly memory.