Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Burn Injuries

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

The effect of nitrile gloves on temperature perception during hot water immersion.

Burns : journal of the International Society for Burn Injuries·2025

Same author

KECORT Study: An International e-Delphi Study on the Treatment of KEloids Using Intralesional CORTicosteroids in Clinical Practice.

American journal of clinical dermatology·2024

Same author

Cumulative sum (CUSUM) analysis: A 10 year experience of outcome monitoring in a regional burn centre.

Burns : journal of the International Society for Burn Injuries·2024

Same author

An eighteen-year review of intensive care requirements for paediatric burns in a regional burns service.

Journal of plastic, reconstructive & aesthetic surgery : JPRAS·2024

Same author

Hydroxypyridone anti-fungals selectively induce myofibroblast apoptosis in an in vitro model of hypertrophic scars.

European journal of pharmacology·2024

Same author

Phenotypic screening identifies hydroxypyridone anti-fungals as novel medicines for the prevention of hypertrophic scars.

European journal of pharmacology·2022

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

Published on: February 23, 2024

Pruritus in burns: review article.

Ioannis Goutos¹, Peter Dziewulski, Patricia M Richardson

¹Plastic Surgery Department, Stoke Mandeville Hospital, Buckinghamshire, United Kingdom.

Journal of Burn Care & Research : Official Publication of the American Burn Association

|January 24, 2009

Summary

Pruritus, or itching, is a common burn wound symptom. Effective treatments include antihistamines and nerve stimulation, but more research is needed for better burn itch relief.

More Related Videos

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Published on: November 6, 2018

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Published on: August 23, 2022

Related Experiment Videos

Last Updated: Jun 26, 2026

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

A Swine Burn Model for Investigating the Healing Process in Multiple Depth Burn Wounds

Published on: February 23, 2024

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment

Published on: November 6, 2018

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Rat Burn Model to Study Full-Thickness Cutaneous Thermal Burn and Infection

Published on: August 23, 2022

Area of Science:

Dermatology and Neuroscience
Burn wound management
Pruritus pathophysiology

Background:

Pruritus (itching) is a frequent and distressing symptom associated with burn wounds.
Advances in neuroanatomy and neurophysiology have identified mediators and pathways of itch transmission.
Current therapeutic approaches for burn pruritus are often based on small-scale studies.

Purpose of the Study:

To review current therapeutic strategies for managing pruritus in burn patients.
To highlight the need for further research in the under-investigated area of burn pruritus.

Main Methods:

Review of existing literature on burn pruritus treatments.
Analysis of studies targeting peripheral and central nervous system components of itch.
Evaluation of evidence for various pharmacological and non-pharmacological interventions.

Main Results:

Established treatments like antihistamines, doxepin, massage, and transcutaneous electrical nerve stimulation show effectiveness.
Gabapentin and ondansetron show preliminary evidence of efficacy in recent studies.
The field of burn pruritus management remains under-researched.

Conclusions:

Several strategies can effectively manage burn pruritus, targeting neurological pathways.
Further large-scale studies are essential to establish evidence-based treatment regimens.
Improved management of burn pruritus is needed to alleviate patient distress.