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[Evaluation of HCl-induced gastric mucosal lesions using a computer image processing system].

T Suzuki¹, M Kagoshima, H Shimada

¹Department of Clinical Pharmacology, School of Pharmaceutical Sciences, Kitasato University, Tokyo, Japan.

Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica

|August 1, 1991

Summary

Hydrochloric acid (HCl) solutions in rats induce gastric mucosal lesions, with higher concentrations causing deeper damage. This study establishes optimal conditions for testing anti-ulcer agents by correlating macroscopic and microscopic lesion characteristics.

Area of Science:

Gastroenterology
Toxicology
Pathology

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