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Published on: March 28, 2025
The diagnosis and management of supraaortic arterial dissections
Manu S Goyal1, Colin P Derdeyn
1Department of Neurology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Insights
Recent advances show supraaortic arterial dissections are a key cause of stroke. Diagnosis and management require tailored imaging and treatment, often involving a multidisciplinary approach for best outcomes.
Area of Science:
- Vascular Neurology
- Neuroradiology
- Interventional Cardiology
Background:
- Supraaortic arterial dissections, affecting carotid and vertebral arteries, are increasingly recognized as significant causes of stroke and subarachnoid hemorrhage.
- Minor trauma combined with underlying arteriopathy is a frequent etiology.
- The diverse pathological changes post-dissection complicate accurate imaging diagnosis.
Purpose of the Study:
- To review recent advancements in the understanding of supraaortic arterial dissections.
- To discuss contemporary diagnostic modalities for these dissections.
- To outline current management strategies for supraaortic arterial dissections.
Main Methods:
- Review of current literature on supraaortic arterial dissections.
- Analysis of diagnostic imaging techniques including ultrasound, MRI/MRA, CTA, and DSA.
- Evaluation of treatment options ranging from antiplatelet therapy to endovascular interventions.
Main Results:
- Imaging diagnosis necessitates tailoring modalities (ultrasound, MRI, CTA, DSA) to individual patient profiles.
- Treatment strategies are variable, encompassing antiplatelet agents, endovascular techniques, and surgical interventions.
- Conservative management is often optimal for cervical dissections, while ruptured dissecting aneurysms demand urgent intervention.
Conclusions:
- The diagnosis and management of supraaortic arterial dissections present considerable complexity.
- A variable, multidisciplinary approach is crucial for optimizing patient outcomes.
- Further research is needed to guide treatment decisions, particularly for stroke secondary to arterial dissection.
Purpose Of Review:
To review recent advances in understanding supraaortic arterial dissections and their diagnosis and management.
Recent Findings:
Dissection of the supraaortic arteries, including the extracranial carotid and vertebral arteries and intracranial arteries, is increasingly identified as an important cause of stroke and subarachnoid hemorrhage. The most common cause likely involves minor trauma with preexisting arteriopathy. The imaging diagnosis of dissection is complicated by the wide range of pathological changes that occur after dissection. Modalities include ultrasound, magnetic resonance imaging and angiography, computed tomography angiography, and digital subtraction angiography. The choice of method is best tailored to each patient individually. Similarly, treatments may vary from antiplatelet medications to complex endovascular techniques. There are limited data to guide treating patients with strokes due to arterial dissections. Conservative management is likely optimal for most patients with cervical dissections, endovascular treatments being reserved for the rapidly deteriorating patient only. However, patients with subarachnoid hemorrhage due to rupture of a dissecting aneurysm require urgent endovascular or surgical treatment of the aneurysm.
Summary:
The diagnosis and management of supraaortic arterial dissections is complex, and a variable multidisciplinary approach will likely yield the best outcome.
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