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Salicylic acid disposition in children with rheumatoid arthritis
N Barzaghi1, G Lamedica, G Gatti
1Department of Internal Medicine and Therapeutics, University of Pavia, Italy.
Fundamental & Clinical Pharmacology
|January 1, 1991
Abstract:
The plasma level profile of SA and SUA after a single oral dose of ASA was studied in 8 children with juvenile rheumatoid arthritis, aged 3.5-15.0 years. Pharmacokinetic parameters were on average similar to those reported in the literature for adult subjects, although a somewhat larger intersubject variability was found.