Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Abuse and Addiction: Pharmacological Phenomena01:15

Drug Abuse and Addiction: Pharmacological Phenomena

Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not necessarily...
Drug Dependence01:17

Drug Dependence

Medications are typically administered to achieve therapeutic effects. Some drugs can modify an individual's mood and perception, frequently resulting in various enjoyable experiences. However, this can result in drug dependency, a condition marked by continuous drug use despite potential negative consequences. Drug dependency primarily falls into two categories: psychological and physical dependence. Psychological dependence occurs when the pleasurable feelings induced by the drug...
Substance Use Disorders Affecting Sleep01:24

Substance Use Disorders Affecting Sleep

Substance use disorders involve a pattern of using drugs more extensively than intended and continuing use despite harmful consequences. This includes legal substances like alcohol and nicotine, as well as illegal drugs. These disorders often involve both physical and psychological dependence, reflecting compulsive use of substances that significantly alter thoughts, feelings, and behaviors, contributing to a major public health issue.
Understanding the concepts of physical dependence,...
Generalized Anxiety Disorder01:30

Generalized Anxiety Disorder

Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
Anxiety: Overview01:18

Anxiety: Overview

Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Episode of major depression refractory to pharmacotherapy.

The West Indian medical journal·2007
Same author

Treatment of postpsychotic depression with sertraline in patients with schizophrenia.

Bratislavske lekarske listy·2006
Same author

[Changes in the endocrine system in the course of sulpiride therapy].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego·2002
Same author

[Anxiety-depressive neurosis in ambulatory treatment conditions].

Wiadomosci lekarskie (Warsaw, Poland : 1960)·1995
Same author

[Alcoholic withdrawal delirium].

Wiadomosci lekarskie (Warsaw, Poland : 1960)·1995
Same author

[Use of lithium salts in psychiatry].

Wiadomosci lekarskie (Warsaw, Poland : 1960)·1993
Same journal

Imunological aspects of kidney retransplantation.

Bratislavske lekarske listy·2024
Same journal

The effect of lengthening of the percutaneous implant in the surgical treatment of Th-L ankylosed spine fractures: 4 segment fixation versus 5 to 8 segment fixation.

Bratislavske lekarske listy·2024
Same journal

Prostate cancer in Slovakia: last decade overview.

Bratislavske lekarske listy·2024
Same journal

Cancer epidemiology in Slovakia.

Bratislavske lekarske listy·2024
Same journal

Peculiarities of nutritional support in patients with neoplasms of the hepatopancreatoduodenal zone as a component of intensive therapy in the postoperative period.

Bratislavske lekarske listy·2024
Same journal

A comparative review of coronary computed tomography angiography and myocardial perfusion imaging.

Bratislavske lekarske listy·2024
See all related articles

Related Experiment Video

Updated: Jun 26, 2026

A Conflict Model of Reward-seeking Behavior in Male Rats
06:11

A Conflict Model of Reward-seeking Behavior in Male Rats

Published on: February 20, 2019

An uncontrollable gambling addiction.

L T Ros1

  • 1Department of Neurosurgery, Central University Teaching Hospital with Policlinic, Armed Forces School of Medicine, Independent Public Health Care Institution, Warszawa, Poland. bll@fmed.uniba.sk

Bratislavske Lekarske Listy
|January 27, 2009
PubMed
Summary
This summary is machine-generated.

This study highlights gambling disorder as a potential addiction. Treatment with psychotherapy and sertraline (a selective serotonin reuptake inhibitor) led to complete remission of obsessive-compulsive syndrome symptoms.

More Related Videos

Transcranial Direct Current Stimulation for Online Gamers
06:01

Transcranial Direct Current Stimulation for Online Gamers

Published on: November 9, 2019

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Related Experiment Videos

Last Updated: Jun 26, 2026

A Conflict Model of Reward-seeking Behavior in Male Rats
06:11

A Conflict Model of Reward-seeking Behavior in Male Rats

Published on: February 20, 2019

Transcranial Direct Current Stimulation for Online Gamers
06:01

Transcranial Direct Current Stimulation for Online Gamers

Published on: November 9, 2019

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

Area of Science:

  • Psychiatry
  • Neuroscience

Background:

  • Gambling disorder is increasingly recognized as a behavioral addiction.
  • Obsessive-compulsive syndrome (OCS) can co-occur with addiction, complicating treatment.
  • Selective serotonin reuptake inhibitors (SSRIs) are a common pharmacotherapy for OCS.

Observation:

  • A patient diagnosed with gambling disorder also presented with obsessive-compulsive syndrome.
  • The patient underwent a treatment regimen combining individual psychotherapy with sertraline, gradually increasing the dosage to approximately 200 mg daily.
  • This systematic treatment approach resulted in a complete remission of the patient's OCS symptoms.

Findings:

  • The successful treatment of OCS symptoms in a patient with gambling disorder suggests a potential link between the two conditions.
  • The effectiveness of sertraline, a selective serotonin reuptake inhibitor (SSRI), in achieving remission supports its role in managing OCS.
  • Indirect evidence indicates a significant role for sertraline in the underlying mechanisms of OCS.

Implications:

  • Sertraline demonstrates safety and efficacy in treating obsessive-compulsive syndrome, even in the context of co-occurring behavioral addictions.
  • This case underscores the importance of addressing comorbid psychiatric conditions like OCS in patients with addiction.
  • Further research into the neurobiological links between gambling disorder and OCS may reveal novel therapeutic targets.