[Mycotic aneurysm and renal transplant. A case report]

L Taksin1, S Mallick, O Frachet

  • 1Service d'urologie, CHU Côte-de-Nacre, avenue Côte-de-Nacre, 14000 Caen, France. liotak@yahoo.fr

Insights

A rare Candida infection after kidney transplant caused an arterial aneurysm. Treatment involved removing the transplant, excising the aneurysm, and bypass surgery, highlighting the need for antifungal therapy and surgical intervention.

Area of Science:

  • Nephrology
  • Transplant Surgery
  • Infectious Diseases

Background:

  • Renal transplantation is a life-saving procedure, but susceptible to complications.
  • Fungal infections, particularly Candida, pose a significant risk post-transplant.
  • Arterial aneurysms are a rare but severe complication following renal transplant.

Observation:

  • A 58-year-old patient developed a Candida-induced arterial aneurysm three weeks after a third renal transplant.
  • Candida albicans was identified in the preservation solution used for the transplanted kidney.
  • Bacteriologic cultures from the patient were positive for Candida.

Findings:

  • The arterial aneurysm was directly linked to a Candida infection.
  • Treatment necessitated transplant nephrectomy, aneurysm excision, and iliac bypass with a homograft.
  • Positive Candida cultures from preservation solutions mandate prompt antifungal treatment.

Implications:

  • Early detection and management of Candida infections are crucial in renal transplant recipients.
  • Arterial aneurysms secondary to fungal infections require aggressive surgical intervention.
  • Transplant nephrectomy is often necessary in cases of severe fungal-related vascular complications.

Related Concept Videos

Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...
Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...