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Updated: Jun 26, 2026

Using SCOPE to Identify Potential Regulatory Motifs in Coregulated Genes
Published on: May 31, 2011
MOTIFATOR: detection and characterization of regulatory motifs using prokaryote transcriptome data
Evert-Jan Blom1, Jos B T M Roerdink, Oscar P Kuipers
1Molecular Genetics, Groningen Biomolecular Sciences, University of Groningen, PO Box 800, 9700 AV Groningen, The Netherlands.
Summary:
Unraveling regulatory mechanisms (e.g. identification of motifs in cis-regulatory regions) remains a major challenge in the analysis of transcriptome experiments. Existing applications identify putative motifs from gene lists obtained at rather arbitrary cutoff and require additional manual processing steps. Our standalone application MOTIFATOR identifies the most optimal parameters for motif discovery and creates an interactive visualization of the results. Discovered putative motifs are functionally characterized, thereby providing valuable insight in the biological processes that could be controlled by the motif.
Availability:
MOTIFATOR is freely available at http://www.motifator.nl.
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