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Published on: February 15, 2022
[Ocular toxicity induced by medication]
1Servicio de Oftalmología, Hospital Virgen del Camino, Pamplona 31008, Spain. andres.garralda.luquin@cfnavarra.es
Abstract:
This paper analyses ocular toxicity induced by four groups of systemic medicines: tamoxifen, chloroquine and derivatives, anticholinergics and tamsulosin. Our main aim is to provide some practical rules that will be of use in the everyday management of patients receiving these treatments, rather than to examine the mechanisms by which each of these medicines act.
Insights
This study outlines practical management rules for ocular toxicity caused by tamoxifen, chloroquine, anticholinergics, and tamsulosin. It focuses on clinical application rather than underlying mechanisms for better patient care.
Area of Science:
- Ophthalmology
- Pharmacology
- Toxicology
Context:
- Systemic medications can cause ocular side effects.
- Four drug classes are frequently associated with ocular toxicity.
- Clinical guidelines for managing these toxicities are needed.
Purpose:
- To provide practical management strategies for ocular toxicity.
- To guide clinicians in managing patients on specific systemic drugs.
- To focus on clinical application over mechanistic explanations.
Summary:
- Analyzes ocular toxicity from tamoxifen, chloroquine and derivatives, anticholinergics, and tamsulosin.
- Offers practical rules for everyday patient management.
- Distinguishes clinical management from mechanistic studies.
Impact:
- Aids clinicians in identifying and managing drug-induced ocular toxicities.
- Improves patient outcomes by providing evidence-based management protocols.
- Enhances understanding of ocular side effects for systemic medications.
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