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Kayser-Fleischer like ring in autoimmune chronic active hepatitis
S A Zargar1, B R Thapa, A Sahni
1Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh.
Summary
Kayser-Fleischer rings typically indicate Wilson disease. This case highlights a similar ring in a child with autoimmune chronic active hepatitis, expanding differential diagnoses.
Area of Science:
- Hepatology
- Ophthalmology
- Pediatrics
Background:
- Kayser-Fleischer rings are a hallmark diagnostic sign of Wilson disease, a genetic disorder of copper metabolism.
- Wilson disease requires prompt diagnosis and treatment to prevent severe liver and neurological damage.
Observation:
- A 9-year-old boy presented with symptoms suggestive of liver disease.
- Ophthalmic examination revealed a Kayser-Fleischer-like ring in the cornea.
Findings:
- The patient was diagnosed with autoimmune chronic active hepatitis.
- The presence of a Kayser-Fleischer-like ring was noted, which is atypical for this condition.
Implications:
- This case broadens the differential diagnosis for Kayser-Fleischer rings beyond Wilson disease.
- It underscores the importance of considering other conditions, such as autoimmune hepatitis, in pediatric patients presenting with these rings.
- Further investigation into the etiology of such rings in non-Wilson disease patients is warranted.