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Related Experiment Video

Updated: Jun 26, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

Persistent delirium predicts greater mortality.

Dan K Kiely1, Edward R Marcantonio, Sharon K Inouye

  • 1Institute for Aging Research, Hebrew SeniorLife, Boston, Massachusetts 02131-1097, USA. kiely@hrca.harvard.edu

Journal of the American Geriatrics Society
|January 28, 2009
PubMed
Summary
This summary is machine-generated.

Persistent delirium in postacute care patients significantly increases 1-year mortality risk. Early resolution of delirium is associated with a reduced risk of death, highlighting the importance of timely intervention for these vulnerable patients.

Related Experiment Videos

Last Updated: Jun 26, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

Area of Science:

  • Gerontology
  • Critical Care Medicine
  • Psychiatry

Background:

  • Delirium is a common and serious condition in postacute care (PAC) patients.
  • The long-term impact of persistent delirium on mortality in this population is not well understood.

Purpose of the Study:

  • To investigate the association between persistent delirium and 1-year mortality in newly admitted PAC patients.
  • To identify if persistent delirium is an independent predictor of mortality.

Main Methods:

  • Observational cohort study of 412 PAC patients with delirium at admission.
  • Delirium assessed using the Confusion Assessment Method at baseline and follow-up (2, 4, 12, 26 weeks).
  • 1-year mortality determined via National Death Index, medical records, and proxy interviews, adjusting for covariates.

Main Results:

  • Approximately one-third of patients remained delirious at 6 months.
  • Cumulative 1-year mortality was 39%.
  • Persistent delirium independently predicted a 2.9-fold increased risk of 1-year mortality (95% CI 1.9-4.4), irrespective of dementia status.

Conclusions:

  • Persistent delirium is a significant, independent predictor of 1-year mortality in PAC patients.
  • Resolution of delirium was associated with diminished mortality risk.
  • This finding underscores the need for effective delirium management strategies in PAC settings.