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Related Concept Videos

Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Pigmentation01:19

Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Papillary Dermis01:11

Papillary Dermis

Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen and...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Changes in Skin Color: Clinical Perspectives01:14

Changes in Skin Color: Clinical Perspectives

The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...

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Related Experiment Video

Updated: Jun 26, 2026

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

[Prurigo].

Annabel Maruani1, Mahtab Samimi, Gérard Lorette

  • 1Université François-Rabelais Tours, Service de Dermatologie, CHRU de Tours, F-37044 Tours Cedex 9, France. annabel.maruani@univ-tours.fr

Presse Medicale (Paris, France : 1983)
|January 28, 2009
PubMed
Summary

Prurigo management depends on whether it is acute or chronic. Acute prurigo is often caused by parasites, while chronic prurigo may indicate underlying skin or internal conditions requiring investigation and treatment.

Area of Science:

  • Dermatology
  • Internal Medicine

Background:

  • Prurigo encompasses diverse clinical, pathological, and etiological conditions.
  • Management strategies differ significantly between acute and chronic prurigo presentations.

Purpose of the Study:

  • To differentiate diagnostic and therapeutic approaches for acute versus chronic prurigo.
  • To highlight the importance of identifying underlying causes for prurigo management.

Main Methods:

  • Review of clinical presentations, etiologies, and diagnostic considerations for prurigo.
  • Emphasis on targeted complementary examinations based on suspected underlying pathologies.

Main Results:

  • Acute prurigo is predominantly associated with parasitic or insect-related causes.

Related Experiment Videos

Last Updated: Jun 26, 2026

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment
06:47

Effects of Exposure of Formaldehyde to a Rat Model of Atopic Dermatitis Induced by Neonatal Capsaicin Treatment

Published on: September 27, 2017

  • Chronic prurigo can be linked to dermatological diseases or serve as a marker for internal pathologies.
  • Idiopathic chronic prurigo is the most common form, necessitating ongoing monitoring for potential disease development.

    • Conclusions:

    • Effective prurigo treatment requires addressing the root cause, whether dermatological or systemic.
    • Symptomatic relief of pruritus, via topical or systemic treatments, is a crucial adjunct to underlying disease management.