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Updated: Jun 26, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
[Intricated asthma tracheomalacia: diagnosis and therapeutic aspects]
N Beydon1, I Menier, L Hovloet-Vermaut
1Unité fonctionnelle de pneumologie pédiatrique, AP-HP, hôpital Robert-Debré, 48, boulevard Sérurier, 75019 Paris, France. nicole.beydon@rdb.aphp.fr
Insights
A novel positive pressure ventilation technique combined with physiotherapy effectively treated a child with severe asthma and tracheomalacia. This approach resolved respiratory issues, preventing further hospitalizations.
Area of Science:
- Pediatrics
- Pulmonology
- Medical Case Reports
Background:
- Difficult-to-treat asthma in children presents significant clinical challenges.
- Co-existing conditions like tracheomalacia can complicate asthma management.
- Standard treatments may be insufficient for complex pediatric respiratory cases.
Observation:
- A young girl experienced recurrent severe respiratory distress, consolidations, and atelectasis requiring intensive care.
- Despite multiple hospitalizations and conventional asthma therapies, her condition persisted.
- Differential diagnosis revealed severe tracheomalacia alongside persistent asthma.
Findings:
- Positive pressure ventilation via a mouthpiece, coupled with active respiratory physiotherapy, proved effective.
- This non-invasive approach successfully cleared atelectasis and resolved acute respiratory episodes.
- The treatment strategy eliminated the need for further hospitalizations.
Implications:
- Highlights the importance of considering tracheomalacia in refractory pediatric asthma.
- Suggests positive pressure ventilation and physiotherapy as a viable therapeutic option for complex cases.
- Emphasizes an open-minded approach to unconventional treatments in pediatric respiratory medicine.
Abstract:
An asthmatic girl was first hospitalized at age 2(9/12) years because of dyspnoea, lung consolidations and/or atelectasis, and rattling. Between ages 2(9/12) and 6(2/12) years, she required three hospitalizations in ICU out of nine hospitalizations for the same symptoms. Differential diagnosis of this difficult to treat asthma disclosed severe tracheomalacia and persistent asthma. Treatments given according to the clinical, radiological and functional findings failed to decrease frequency and severity of acute respiratory episodes. Eventually, positive pressure ventilation delivered at airway opening (via a mouthpiece) associated to active respiratory physiotherapy succeeded in removing atelectasis and quickly cured the five following acute episodes without any further hospitalization. This case report is about diagnosis procedure, intricate asthma and tracheomalacia, and open mind to unusual therapeutics that may disclose potential help.
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