Related Experiment Video
Updated: Jun 26, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
Is there a correlation between venlafaxine therapy during pregnancy and a higher incidence of necrotizing
Markus Treichel1, Katharina Schwendener Scholl, Ulf Kessler
1Department of Neonatology, Children's Hospital, University of Berne, Berne, Switzerland.
Background:
Novel antidepressant drugs are increasingly used by women of child bearing age. However, potentially harmful effects on fetus and newborn remain unknown.
Methods:
Case report and literature review.
Results:
We present preterm twins whose mother was treated with venlafaxine, a nonselective serotonin reuptake inhibitor, throughout pregnancy until delivery. The twins developed neonatal necrotizing enterocolitis.
Conclusion:
The question whether there might be a correlation between maternal serotonin reuptake inhibitor therapy and neonatal necrotizing enterocolitis is discussed.

