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Updated: Jun 26, 2026

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

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Published on: May 1, 2015

Congenital pulmonary lymphangiectasis.

Zuo-Yuan Xiao¹, Yu Tao, Xin-Yi Tang

¹Department of General Pediatrics, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. xiaozy2@126.com

World Journal of Pediatrics : WJP

|January 28, 2009

Summary

This summary is machine-generated.

Congenital pulmonary lymphangiectasis (CPL) is a rare condition causing severe respiratory issues in newborns. This case highlights the rapid, fatal progression of CPL, emphasizing the need for accurate diagnosis.

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Area of Science:

Neonatal Medicine
Pediatric Pathology
Pulmonary Medicine

Background:

Congenital pulmonary lymphangiectasis (CPL) is a rare congenital anomaly involving dilated pulmonary lymphatic vessels.
Neonatal CPL often presents with severe respiratory compromise and high mortality rates.

Observation:

A male infant presented with cyanosis and cardiac arrest shortly after birth.
Symptoms persisted despite artificial ventilation, leading to death from hypoxemic cardiac failure within an hour.

Findings:

Autopsy revealed dilated lymphatic vessels in the lungs.
Diagnoses included CPL, atelectasis, amniotic fluid inhalation, hepatic cell degeneration, and scrotal edema.

Implications:

Accurate differentiation of CPL from other neonatal respiratory conditions is crucial for prognosis.
This case underscores the critical nature and poor outcomes associated with severe neonatal CPL.