Related Experiment Video

Updated: Jun 26, 2026

Generalized Psychophysiological Interaction (PPI) Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
09:38

Generalized Psychophysiological Interaction (PPI) Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease

Published on: November 14, 2017

The complex interaction between APOE promoter and AD: an Italian case-control study

Alessandra Bizzarro1, Davide Seripa, Adele Acciarri

  • 1Institute of Neurology, Department of Neuroscience, Catholic University School of Medicine, Rome, Italy. alessandrabizzarro@libero.it

European Journal of Human Genetics : EJHG
|January 29, 2009
PubMed
Summary

This study identifies specific APOE gene promoter single nucleotide polymorphisms (SNPs) as risk factors for Alzheimer's disease (AD), independent of APOE e4 status. Findings confirm rs449647 A/A genotype as an AD risk factor in Italy.

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