Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ectopic hematopoiesis in the human iris.

J R Wolter1, B Schnitzer, A Wieringa

  • 1Department of Ophthalmology, University of Michigan Medical Center, Ann Arbor.

International Ophthalmology
|July 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

How to perform pharmacokinetic research of antimicrobial drugs in critically ill patients undergoing continuous renal replacement therapy: a scoping review of all relevant pharmacokinetic factors.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases·2025
Same author

Concentrations of venlafaxine and its main metabolite O-desmethylvenlafaxine during pregnancy.

Journal of clinical pharmacy and therapeutics·2014
Same author

The management of advanced rhabdomyosarcoma of the upper eyelid.

Journal of pediatric ophthalmology and strabismus·2014
Same author

ALK-positive diffuse large B-cell lymphoma with ALK-Clathrin fusion belongs to the spectrum of pediatric lymphomas.

Leukemia·2005
Same author

Primary diagnosis of whipple disease manifesting as lymphadenopathy: use of polymerase chain reaction for detection of Tropheryma whippelii.

American journal of clinical pathology·2002
Same author

Waldenström macroglobulinemia caused by extranodal marginal zone B-cell lymphoma: a report of six cases.

American journal of clinical pathology·2001
Same journal

Pulsed accelerated corneal cross-linking for pediatric keratoconus: a prospective study from the Indian subcontinent.

International ophthalmology·2026
Same journal

Short-term OCT-based evaluation of corneal epithelial remodeling with two silicone hydrogel bandage contact lenses after t-PRK.

International ophthalmology·2026
Same journal

Central and peripheral retinal image quality in high myopia: effects of corneal and intraocular refractive correction.

International ophthalmology·2026
Same journal

Mitochondrial insufficiencies and neuroprotection in glaucoma.

International ophthalmology·2026
Same journal

Accuracy of new-generation intraocular lens formulas in IOL power calculation for cataract extraction combined with vitrectomy.

International ophthalmology·2026
Same journal

Screen time, strained eyes: knowledge and attitudes toward rising screen hours and ocular health among adults aged 20-30 in sri lanka.

International ophthalmology·2026
See all related articles

Diabetic eye disease can lead to unusual findings, like hematopoietic cells in the iris. This case highlights a rare pathological discovery in a patient with severe diabetic retinopathy and glaucoma.

Area of Science:

  • Ophthalmology
  • Hematology
  • Pathology

Background:

  • Diabetic retinopathy is a leading cause of vision loss, often associated with neovascularization and complications.
  • Central retinal vein occlusion (CRVO) can cause severe visual impairment and secondary glaucoma.
  • Previous ocular surgeries, including vitrectomy and cataract extraction, can alter the ocular environment.

Observation:

  • A 35-year-old male with diabetes presented with absolute hemorrhagic glaucoma.
  • The patient's eye was enucleated due to complications following CRVO, vitrectomy, retinal detachment repair, and cataract extraction.
  • Pathological examination revealed hematopoietic islands of erythroblastic precursor cells within the iris.

Findings:

  • The presence of erythroblastic precursor cells with mitotic activity in the iris is a rare pathological finding.

Related Experiment Videos

  • These hematopoietic islands suggest extramedullary hematopoiesis or a similar process occurring within the ocular tissues.
  • The distorted iris morphology was noted in conjunction with these cellular inclusions.

    • Implications:

    • This finding expands the understanding of potential ocular manifestations in advanced diabetic disease and severe ocular trauma.
    • It suggests that the eye, under specific pathological conditions, may exhibit hematopoietic activity.
    • Further research is warranted to elucidate the mechanisms and clinical significance of such intraocular hematopoietic findings.