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Peripheral Artery Disease I: Introduction

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...

Peripheral Artery Disease V: Postoperative Nursing Management

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

Peripheral Artery Disease IV: Nursing Management

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...

Arteries of Lower Limbs

Arteries of Lower Limbs

The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular artery,...

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Related Experiment Video

Updated: Jun 26, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Peripheral artery leiomyosarcoma.

Sujit Vijay Sakpal¹, Rohin Mehta, Nitin Babel

¹Department of Surgery, Saint Barnabas Medical Center, Livingston, NJ 07039, USA.

Journal of Vascular Surgery

|January 29, 2009

Summary

This summary is machine-generated.

Vascular leiomyosarcomas are rare tumors. This case report reviews peripheral arterial leiomyosarcomas, focusing on the profunda femoris artery, and discusses diagnosis and treatment.

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Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

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Minimally Invasive Isolated Limb Perfusion (MI-ILP) for Locally Advanced Melanomas and Sarcomas of the Extremity

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Published on: January 31, 2025

Area of Science:

Oncology
Vascular Surgery
Pathology

Background:

Vascular leiomyosarcomas are rare malignancies, accounting for 0.001% of all cancers.
Venous leiomyosarcomas are more common than arterial types, frequently arising in the inferior vena cava (IVC).
Arterial leiomyosarcomas typically affect great vessels, with fewer than 50% occurring in peripheral circulation.

Observation:

This report details a rare case of arterial leiomyosarcoma involving the profunda femoris artery.
Only seven cases of femoral artery leiomyosarcomas have been previously documented in medical literature.
Peripheral arterial leiomyosarcomas present unique diagnostic and therapeutic challenges.

Findings:

The study provides a comprehensive review of peripheral arterial leiomyosarcomas.
Key aspects covered include tumor distribution, clinical presentation, and diagnostic methods (radiological and histological).
The review also addresses staging and treatment strategies for these rare tumors.

Implications:

This case and review contribute to understanding the rarity and clinical behavior of peripheral arterial leiomyosarcomas.
Enhanced knowledge of diagnosis and staging can improve patient outcomes.
The findings may guide future research and clinical management protocols for vascular leiomyosarcomas.