[Three case reports of metastatic germ cell tumors in the lumbar vertebra during first-line chemotherapy]
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Updated: Jun 26, 2026

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
Published on: December 27, 2024
Masato Dobashi1, Shigehiro Son, Masaomi Ikeda
1The Department of Urology, Kitasato University School of Medicine.
Abstract:
We report three patients with germ cell tumors whose diagnosis was confirmed in the progress of the first-line chemotherapy regimen as metastatic cancer in the lumbar vertebra. Two of the 3 cases were mixed-type nonseminoma, and the other case was an extragonadal tumor. After the first-line chemotherapy regimen, the patients underwent salvage chemotherapy using Paclitaxel either with or without irradiation. We confirmed the efficacy that the bone metastasis had completely been resolved and the lymph node metastasis was significantly reduced after the completion of all treatments.
