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Strategy for incorporating molecular and cytogenetic markers into acute myeloid leukemia therapy

Mark G Frattini1, Peter G Maslak

  • 1Leukemia Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

Journal of the National Comprehensive Cancer Network : JNCCN
|January 30, 2009
PubMed

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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...