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Updated: Jun 26, 2026

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
Published on: April 20, 2018
Evaluation and management of the unknown primary carcinoma of the head and neck
1Department of Thoracic/Head and Neck Surgery, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77230-1402, USA.
Abstract:
Squamous cell carcinoma of unknown primary origin in the head and neck is encountered as a recurring clinical problem in head and neck cancer clinics, affecting 3% to 25% of patients. This article describes the clinical presentation, appropriate evaluation, and treatment strategies for this important subgroup. Treatment--best carried out with multidisciplinary teams of specialists experienced in the care of head and neck cancer patients--is curative for most of these patients.
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