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Cytosine arabinoside chemotherapy for acute megakaryocytic leukemia in a cat

T A Hamilton1, W B Morrison, D B DeNicola

  • 1Department of Veterinary Clinical Sciences, Purdue University, West Lafayette, IN 47905.

Myeloproliferative disease in a cat was characterized by severe, nonregenerative anemia, circulating blast cells, and proliferation of bizarre megakaryoblasts in the bone marrow. The number of circulating platelets was markedly higher than normal at initial examination. Chemotherapy with cytosine arabinoside was successful in inducing complete remission and maintaining survival for 122 days.

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