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Updated: Jun 26, 2026

Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease
Published on: April 4, 2018
The DICS repository: module-assisted analysis of disease-related gene lists
Sabine Dietmann1, Elisabeth Georgii, Alexey Antonov
1Institute for Bioinformatics and Systems Biology, German Research Center for Environmental Health, Ingolstädter Landstrasse 1, D-85764 Neuherberg, Germany. sabine.dietmann@googlemail.com
Summary:
The DICS database is a dynamic web repository of computationally predicted functional modules from the human protein-protein interaction network. It provides references to the CORUM, DrugBank, KEGG and Reactome pathway databases. DICS can be accessed for retrieving sets of overlapping modules and protein complexes that are significantly enriched in a gene list, thereby providing valuable information about the functional context.
Availability:
Supplementary information on datasets and methods is available on the web server http://mips.gsf.de/proj/dics.

