Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reinnervation of developing rat molars.

C D Johnston1, P D Owens

  • 1School of Clinical Dentistry, Queen's University of Belfast, N. Ireland.

Journal of Anatomy
|June 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Helicobacter pylori Chronic Infection Selects for Effective Colonizers of Metaplastic Glands.

mBio·2023
Same author

Tracking NSZD mass removal rates over decades: Site-wide and local scale assessment of mass removal at a legacy petroleum site.

Journal of contaminant hydrology·2022
Same author

Insights Obtained by Culturing Saccharibacteria With Their Bacterial Hosts.

Journal of dental research·2020
Same author

Effect of compositional heterogeneity on dissolution of non-ideal LNAPL mixtures.

Journal of contaminant hydrology·2016
Same author

Retention in orthodontics.

British dental journal·2015
Same author

Mass discharge assessment at a brominated DNAPL site: Effects of known DNAPL source mass removal.

Journal of contaminant hydrology·2014

Regenerating inferior alveolar nerve (IAN) fibers can reinnervate developing rat molar dentine after injury. Studies show significant dentine reinnervation occurs over 50 days, suggesting an active regeneration process in young animals.

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Odontology

Background:

  • The inferior alveolar nerve (IAN) innervates dental tissues.
  • Understanding nerve regeneration is crucial for dental repair and function.

Purpose of the Study:

  • To investigate the capacity of regenerating inferior alveolar nerve (IAN) fibers to reinnervate dentine in developing rat first molar teeth following nerve transection.

Main Methods:

  • Intramandibular transection of the IAN in 20-day-old rats.
  • Estimation of innervated dentinal tubules at 5, 15, 30, and 50 days post-surgery.
  • Light microscopy examination of myelinated axon populations in root canal pulps.

Main Results:

  • Rapid degeneration of pulpal and dentinal axons within 5 days post-transection.

Related Experiment Videos

  • Evidence of pulpal reinnervation by 15 days; dentinal tubule reinnervation reached ~17.7% by 30 days and ~70% of control levels by 50 days.
  • Significant dentine reinnervation occurs over time, indicating regenerative potential.

    • Conclusions:

    • Dentine reinnervation is possible in developing teeth after IAN transection.
    • Regeneration appears faster and more complete in younger animals.
    • The mechanism of reinnervation may be primarily active, not passive.