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Successful pregnancy and cesarean delivery via noninvasive ventilation in mitochondrial myopathy

N Yuan1, Y Y El-Sayed, S J Ruoss

  • 1Department of Pediatrics, Center of Excellence in Pulmonary Biology (Pulmonary Division), Stanford University Medical Center, Palo Alto, CA, USA. nyuan@stanford.edu

Journal of Perinatology : Official Journal of the California Perinatal Association
|January 30, 2009
PubMed

We report a case study of a 22-year-old woman with mitochondrial thymidine kinase 2 deficiency and chronic respiratory failure due to severe neuromuscular weakness requiring noninvasive positive pressure ventilation (NIPPV) since 12 years of age. During pregnancy and cesarean delivery, she was successfully supported with NIPPV. A multidisciplinary team approach should be used in pregnant patients with these disorders with specific attention to management of pulmonary complications, selection of route of delivery, anesthesia, and analgesia.

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