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Updated: Jun 26, 2026

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro

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Antioxidant constituents from Cotoneaster racemiflora.

Shafiullah Khan¹, Naheed Riaz, Nighat Afza

¹Pharmaceutical Research Centre, Karachi, Pakistan.

Journal of Asian Natural Products Research

|January 30, 2009

Summary

A new compound, racemiside, and four known compounds were isolated from Cotoneaster racemiflora. All isolated compounds demonstrated significant antioxidative activities in the DPPH assay.

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Area of Science:

Phytochemistry
Natural Products Chemistry
Pharmacognosy

Background:

Cotoneaster racemiflora is a plant species with potential medicinal properties.
Natural products are a rich source of bioactive compounds with therapeutic potential.

Purpose of the Study:

To isolate and identify chemical constituents from Cotoneaster racemiflora.
To evaluate the antioxidative potential of the isolated compounds.

Main Methods:

Extraction of plant material using ethyl acetate.
Isolation of compounds using chromatographic techniques.
Identification of compounds using spectroscopic methods.
Evaluation of antioxidative activity using the DPPH assay.

Main Results:

A new lignan rhamnoside, racemiside (1), was isolated.
Four known compounds: scopoletin (2), 7,8-dimethoxy-6-hydroxycoumarin (3), 3,3',4'-tri-O-methylellagic acid (4), and cereotagloperoxide (5) were identified.
All isolated compounds exhibited significant antioxidative activities.

Conclusions:

Cotoneaster racemiflora is a source of bioactive lignans and other phenolic compounds.
The isolated compounds, particularly racemiside, possess notable antioxidative properties.
Further research into the pharmacological activities of these compounds is warranted.