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Updated: Jun 26, 2026

Localization of the Locus Coeruleus in the Mouse Brain
Published on: March 7, 2019
Tumor locus moderates anxiety symptoms in a pediatric neuro-oncologic sample
Ethan Moitra1, Carol L Armstrong
1Division of Neuro-oncology, Children's Hospital of Philadelphia, and Department of Psychology, Drexel University, Philadelphia, PA 19102, USA. em742@drexel.edu
Abstract:
Despite the prevalence of pediatric Central Nervous System (CNS) solid tumors, little is understood about patients' disease-related anxiety experience. Data from 25 remitted pediatric CNS tumor patients posttreatment were collected. Significant symptoms of anxiety were reported by 32% of patients. MRI studies showed all anxious patients had right cortical tumors or left cerebellar tumors. Confound analyses suggest these results are not better accounted for by demographic, disease, or treatment variables. These results evidence the risk some pediatric neuro-oncologic patients face for developing significant anxiety symptoms.
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