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Updated: Jun 26, 2026

Laparoscopic Extracorporeal Knot-Tying for Uterine Vessel Occlusion during Hysterectomy with Cervical Cerclage in Large Uteri
Published on: September 12, 2025
Repeat uterine artery embolization following poor results.
Bruce McLucas1, Richard A Reed
1Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. mclucas@ucla.edu
Repeat uterine artery embolization is effective for patients experiencing persistent symptoms after an initial procedure. A second embolization significantly improved symptom relief in most cases, making it a viable option.
Area of Science:
- Interventional Radiology
- Gynecology
Background:
- Uterine artery embolization (UAE) is a common treatment for symptomatic uterine fibroids.
- Some patients do not achieve adequate symptom relief after initial UAE.
Purpose of the Study:
- To evaluate the effectiveness of repeat UAE in patients with inadequate symptom relief following a first procedure.
Main Methods:
- Retrospective chart review of patients who underwent UAE for symptomatic uterine fibroids between 1994 and 2007.
- Success defined by symptom relief questionnaires post-procedure.
- Analysis of patients who opted for a second UAE after initial treatment failure.
Main Results:
- 1058 patients underwent initial UAE; 42 (3.97%) reported unsuccessful symptom relief.
- 39 patients underwent a second UAE.
- 32 of 34 patients (94.1%) reported symptom relief lasting at least six months after the second UAE.
Conclusions:
- Repeat UAE is a highly effective treatment for patients with persistent symptoms after an initial embolization.
- A second UAE should be considered for patients who do not achieve adequate symptom relief from the first procedure.
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