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Related Concept Videos

Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Bacterial Phylum Chlamydiae01:29

Bacterial Phylum Chlamydiae

The phylum Chlamydiae or Chlamydiota is composed of a single order, Chlamydiales. This phylum consists entirely of obligate intracellular parasites that infect eukaryotic hosts. While human pathogens within this group have been studied extensively, the phylum encompasses many species capable of interacting with various eukaryotic organisms. Members of Chlamydiae are typically small cocci, approximately 0.5 μm in diameter, and exhibit a distinctive developmental cycle. As is characteristic of...
Trichomoniasis01:18

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
Genital Herpes01:23

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...

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Updated: Jun 26, 2026

Forward Genetic Approaches in Chlamydia trachomatis
09:03

Forward Genetic Approaches in Chlamydia trachomatis

Published on: October 23, 2013

[Genital chlamydial infection].

Koichi Monden1, Hiromi Kumon

  • 1Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|January 31, 2009
PubMed
Summary

Genital chlamydial infection, caused by Chlamydia trachomatis, often presents asymptomatically. Early detection and treatment are crucial to prevent severe reproductive health complications in women.

Area of Science:

  • Microbiology
  • Public Health
  • Infectious Diseases

Context:

  • Genital chlamydial infection is a significant sexually transmitted disease (STD).
  • Chlamydia trachomatis is the causative agent, leading to various urogenital and pharyngeal infections.
  • Asymptomatic infections are prevalent, affecting approximately 50% of men and 70% of women.

Purpose:

  • To review the pathology, diagnosis, and treatment of genital chlamydial infection.
  • To highlight the public health importance of Chlamydia trachomatis.
  • To emphasize the need for effective detection and management strategies.

Summary:

  • Chlamydia trachomatis causes genital infections with potential for asymptomatic presentation.
  • The infection can lead to urethritis, cervicitis, pharyngitis, and epididymitis.

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Markerless Gene Deletion by Floxed Cassette Allelic Exchange Mutagenesis in Chlamydia trachomatis

Published on: January 30, 2020

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
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A Human Fallopian Tube Model for Investigation of C. trachomatis Infections

Published on: August 11, 2012

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Last Updated: Jun 26, 2026

Forward Genetic Approaches in Chlamydia trachomatis
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Markerless Gene Deletion by Floxed Cassette Allelic Exchange Mutagenesis in Chlamydia trachomatis
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Markerless Gene Deletion by Floxed Cassette Allelic Exchange Mutagenesis in Chlamydia trachomatis

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A Human Fallopian Tube Model for Investigation of C. trachomatis Infections
09:11

A Human Fallopian Tube Model for Investigation of C. trachomatis Infections

Published on: August 11, 2012

  • Women with genital C. trachomatis infection face increased risks of tubal factor infertility and ectopic pregnancy.
  • Impact:

    • Effective detection and treatment are vital for preventing outbreaks.
    • Understanding the pathology, diagnosis, and treatment is essential for public health.
    • Reducing the burden of chlamydial infections improves reproductive health outcomes.