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Updated: Jun 26, 2026

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High-definition Transcranial Direct Current Stimulation over Right Dorsolateral Prefrontal Cortex to Enhance Metacognitive Sensitivity
Published on: September 26, 2025
[Transcranial direct current stimulation--a new tool for human cognitive neuroscience]
Satoshi Tanaka1, Katsumi Watanabe
1Research Center for Advanced Technology and Science, The University of Tokyo.
Brain and Nerve = Shinkei Kenkyu No Shinpo
|January 31, 2009
Summary
Transcranial direct current stimulation (tDCS) offers a non-invasive method to modulate brain activity, enhancing cognitive and motor functions. Its advantages, including low cost and minimal artifacts, make it a valuable tool for research and clinical applications.
Area of Science:
- Neuroscience
- Neuromodulation
- Cognitive Science
Context:
- Transcranial direct current stimulation (tDCS) is an emerging non-invasive brain stimulation technique.
- tDCS utilizes weak electrical currents to modulate neuronal activity in targeted brain regions.
- It is increasingly employed in research with healthy individuals and patient populations.
Purpose:
- To investigate the causal links between brain activity and behavior.
- To explore the potential of tDCS for cognitive and motor enhancement.
- To evaluate tDCS as a complementary tool to existing brain stimulation methods like TMS.
Summary:
- tDCS involves applying direct currents to the scalp to alter cortical excitability, with anodal stimulation increasing and cathodal stimulation decreasing it.
- This technique allows for the study of brain-behavior relationships and has shown promise in enhancing motor and cognitive functions.
- Compared to transcranial magnetic stimulation (TMS), tDCS offers advantages such as reduced artifacts, lower cost, and portability, making it suitable for various research and clinical settings.
Impact:
- tDCS facilitates the investigation of brain function and behavior.
- It holds potential for cognitive enhancement and motor rehabilitation.
- Its safety profile and practical advantages position it as a valuable tool in neuroscience and clinical practice.

