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Updated: Jun 26, 2026

Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats
Published on: June 22, 2017
[Dynamics of the rats higher nervous activity disturbances after partial influence of high energy electrons in high
Abstract:
The dynamics of the disturbances of stabilized motor defensive conditioned reflex of active avoidance in "shuttle-box" in rats after total and partial (the head or body irradiated) influence of high energy electrons in dose 100 Gy was investigated. The head irradiation, the same way as total irradiation, provoked the early effects of disturbances of higher nervous activity, specifically, initial shock-like effect--the "early transient incapacitation" (ETI). The head shielding, on the contrary, prevents these disturbances. At the same times the body irradiation in dose 10 Gy (this dose don't provoke ETI effect) provoked practically the same disturbances of higher nervous activity as the total irradiation. Consequently, in animals irradiated in super-lethal doses the early disturbances of higher nervous activity provoked of direct influence of ionizing radiation to the brain. In animals irradiated in lesser doses these disturbances caused of non direct effects basically.

