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Updated: Jun 26, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

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Published on: December 11, 2016

Projecting future drug expenditures--2009.

James M Hoffman¹, Nilay D Shah, Lee C Vermeulen

¹Pharmaceutical Department, St. Jude Children's Research Hospital, Memphis, TN, USA.

American Journal of Health-System Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists

|January 31, 2009

Summary

U.S. drug spending grew 4% from 2006-2007. Projections for 2009 show modest growth, influenced by generics, safety concerns, and Medicare Part D.

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Area of Science:

Health Economics
Pharmaceutical Policy

Background:

U.S. drug expenditures reached $287 billion in 2007.
Clinic drug spending increased by 9.9% from 2006-2007, outpacing hospital spending.

Purpose of the Study:

To analyze drug expenditure trends in 2007-2008.
To project drug expenditures for 2009.
To identify factors influencing future drug spending.

Main Methods:

Analysis of national drug expenditure data.
Review of factors impacting pharmaceutical markets.
Trend analysis and forecasting.

Main Results:

Total U.S. drug expenditures increased 4.0% from 2006 to 2007.
Clinic drug expenditures rose 9.9% in the same period.
Projected 2009 drug expenditure increases range from 0-3% across settings.

Conclusions:

Generic drugs and safety concerns moderate expenditure growth.
Medicare Part D's long-term impact on drug spending remains under evaluation.
The drug supply chain continues to evolve, potentially impacting specialized therapeutic areas.