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Updated: Jun 26, 2026

Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
Spontaneous and simultaneous multivessel coronary spasm causing multisite myocardial infarction, cardiogenic shock,
Yao-Tsung Chuang1, Kwo-Chang Ueng
1Cardiovascular Study Group, Institute of Medicine, Division of Cardiology, Chung Shan Medical University Hospital, Taichung, Taiwan.
Insights
A rare case of simultaneous anterior and inferior myocardial infarction occurred in a 57-year-old man. Prompt treatment with isosorbide dinitrate successfully relieved coronary artery occlusion.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Variant angina is a condition characterized by chest pain due to coronary artery spasms.
- Myocardial infarction (MI) typically results from prolonged blockage of coronary arteries.
Observation:
- A 57-year-old man with a history of variant angina presented with simultaneous anterior and inferior myocardial infarction.
- The patient also experienced atrioventricular block, cardiogenic shock, and ventricular fibrillation.
Findings:
- Left coronary angiography revealed concurrent occlusion of the left anterior descending and left circumflex arteries.
- Intracoronary isosorbide dinitrate administration successfully relieved these occlusions.
Implications:
- This case highlights a rare presentation of myocardial infarction potentially linked to variant angina.
- It underscores the importance of considering vasospasm in complex MI cases and the efficacy of vasodilators.
Abstract:
A 57-year-old Taiwanese man with a past history of variant angina developed simultaneous anterior and inferior myocardial infarction, atrioventricular block, cardiogenic shock, and eventually ventricular fibrillation. Left coronary angiography revealed simultaneous occlusion of the left anterior descending and the left circumflex coronary arteries, which was relieved by intracoronary administration of isosorbide dinitrate. This is the first report of such a case in the English-language medical literature.
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